The Kisumu County Agri-Nutrition Implementation Strategy (CANIS) has been developed at a time when the world, Kenya, and Kisumu are experiencing challenges to adequate, safe, and nutritious food for their populations. The exploration and use of opportunities for and the benefits of the strategy’s implementation are therefore essential. The agri-nutrition sector affects everyone. It is little wonder that discussions about safe and nutritious foods, genetically modified foods, issues about fertilizer, smart farming, food and nutrition security are being addressed in various forums organised by United Nations, African Union, East African Community, and at the country level. At national and county levels, food and nutrition issues are prioritised under the Fourth Medium Term Plan (MTP 2023–2027) of Kenya Vision 2030 and the Big 4 Agenda, with particular emphasis and focus on increased productivity, irrigation, expansion, and expanded markets.