The interface between information communication technologies (ICTs) and innovation remains largely under-researched. Attempting to bridge this knowledge gap, this cross-sectional study of Kenya’s micro, small and medium establishments examines the role of ICTs in innovation. The study applies Probit estimators to a comprehensive data set of 24,164 micro, small and medium establishments. Generally, the study reveals that the sectors having the highest incidence of innovation are electricity, gas, steam and air conditioning; ICT; education and real estate. Although the minority of establishments generated some innovations, product innovation was the most common type. Generally, information and communication technologies are found to stimulate innovation activity.